Publications

  1. A. Berrocal*, J.E. Sandoval*, N. Khetan*, A. Ma, T. Wang, C. Moore, G.J. Narlikar, H. Li, D.G. Fujimori#, B. Huang#. "Preferential formation of NUP98-KDM5A condensates at specific H3K4me3-rich loci drives leukemogenic gene expression". bioRxiv/2026.03.16.712262 (2026). Preprint
  2. R. Mosadeghi#, D. Foyt, L. Sharp, C. Taylor, N.Q. Tay, S. Oberlin, J. Fan, S. Bourke, M. Kattah, B. Huang#, M.T McManus#. "RainBar: Optical Barcoding for Pooled Live-Cell Imaging with Single-Cell Resolution". bioRxiv/2025.11.04.686676 (2025). Preprint
  3. Y. Chen*, K. Yserentant*, K. Hong*, Y. Kuang, A. Bhowmick, A. Charles-Orszag, S.J. Lord, L. Lu, K. Hou, S.I. Mann, J.B. Grimm, L.D. Lavis, R.D. Mullins, W.F. DeGrado#, B. Huang#. "De novo designed bright, hyperstable rhodamine binders for fluorescence microscopy". bioRxiv/2025.06.25.661379 (2025). Preprint
  4. D. Foyt, D. Brown, S. Zhou, B. Moser, Q. Zhu, Z.J. Gardner, B. Huang. "HybriSeq: probe-based device-free single-cell RNA profiling". Commun. Biol. 1250 (2025). Journal Preprint
  5. K. Meyer, B. Huang, O.D. Weiner, "Emerging roles of transcriptional condensates as temporal signal integrators". Nat Rev Genetics (2025).
  6. Z. Zhou, K. Hong, B. Huang, G.J. Narlikar, "Understanding how genetically encoded tags and crowding agents affect phase separation by heterochromatin protein HP1a". Cell Reports Methods 5, 101029 (2025).
  7. D. Foyt,# Y. Kuang, S. Rehem, K. Yserentant, B. Huang#, "Accessible and accurate cytometry analysis of adherent cells using fluorescence microscopes". Scientific Reports 15, 18691 (2025). Journal Preprint
  8. D. Zheng, B. Huang, "Bridging protein sequences and microscopy images with unified diffusion models". In: 42nd International Conference on Machine Learning. ICML (2025). Conference Preprint CZI Virtual Cell Model Collection
  9. K. Meyer,* K. Yserentant,* R. Cheloor-Kovilakam,* K.M. Ruff, C.I. Chung, X. Shu, B. Huang,# O.D. Weiner#. "YAP charge patterning mediates signal integration through transcriptional co-condensates". Nat. Commun. 16, 7454 (2025). Journal Preprint
  10. D. Gonzalez-Martinez, L. Roth, T. Mumford, J. Guan, Bo Huang, A. Tulpule, T. Bivona, A. Le, R. Doebele, M. Niewiadomska-Bugaj, L. Bugaj, "Oncogenic EML4-ALK assemblies suppress growth factor perception and modulate drug tolerance". Nat. Commun. 15, 9473 (2024).
  11. I.E. Ivanov,*,# E. Hirata-Miyasaki,* T. Chandler,* R. Cheloor-Kovilakam,* Z. Liu, S. Pradeep, C. Liu, M. Bhave, S. Khadka, C. Arias, M.D. Leonetti, B. Huang,# S.B. Mehta#, "Mantis: high-throughput 4D imaging and analysis of the molecular and physical architecture of cells," PNAS Nexus, pgae323 (2024). Journal Preprint
  12. F. Haderk, Y.-T. Chou, L. Cech, C. Fernandez-Mendez, J. Yu, V. Olivas, I.M. Meraz, D.B. Rabago, D.L. Kerr, C. Gomez, D.V. Allegakoen, J. Guan, K.N. Shah, K.A. Herrington, O.M. Gbenedio, S. Nanjo, M. Majidi, W. Tamaki, Y.K. Pourmoghadam, J.K. Rotow, C.E. McCoach, J.W. Riess, J.S. Gutkind, T.T. Tang, L. Post, B. Huang, P. Santisteban, H. Goodarzi, S. Bandyopadhyay, C.J. Kuo, J.P. Roose, W. Wu, C.M. Blakely, J.A. Roth, T.G. Bivona, "Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer". Nat. Commun. 15, 3741 (2024).
  13. E. Khwaja#, Y.S. Song, B. Huang#, "CELL-E: a text-to-image transformer for protein image prediction," In: Research In Computational Molecular Biology. RECOMB 2024. Lecture Notes in Computer Science, v14758. Springer, Cham. (2024). Preceedings Preprint
  14. E. Khwaja#, Y.S. Song, A. Agarunov, B. Huang#, "CELL-E 2: Translating Proteins to Pictures and Back with a Bidirectional Text-to-Image Transformer," In: 37th Neural Information Processing Systems NeurIPS (2023). Conference Preprint
  15. J. Dekker, F. Alber, S. Aufmkolk, B.J. Beliveau, B.G. Bruneau, A.S. Belmont, L. Bintu, A. Boettiger, R. Calandrelli, C.M. Disteche, D.M. Gilbert, T. Gregor, A.S Hansen, B. Huang, D. Huangfu, R. Kalhor, C.S. Leslie, W. Li, Y. Li, J. Ma, W.S. Noble, P.J. Park, J.E. Phillips-Cremins, K.S. Pollard, S.M. Rafelski, B. Ren, Y. Ruan, Y. Shav-Tal, Y. Shen, J. Shendure, X. Shu, C. Strambio-De-Castillia, A. Vertii, H. Zhang, S. Zhong, "Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project," Mol. Cell, 83, 2623 (2023).
  16. J. Zhao*, S. Makhija*, C. Zhou, H. Zhang, Y.Q. Wang, M. Muralidharan, B. Huang#, Y. Cheng#, "Structural insights into the human PA28–20S proteasome enabled by efficient tagging and purification of endogenous proteins," Proc. Nat. Acad. Sci. U.S.A., 119, e2207200119 (2022). Journal Preprint
  17. N.H. Cho, K.C. Cheveralls, A. Brunner, K. Kim, A.C. Michaelis, P. Raghavan, H. Kobayashi, L. Savy, J.Y. Li, H. Canaj, J.Y.S. Kim, E.M. Stewart, C. Gnann, F. McCarthy, J.P. Cabrera, R.M. Brunetti, B.B. Chhun, G. Dingle, M.Y. Hein, B. Huang, S.B. Mehta, J.S. Weissman, R. Gómez-Sjöberg, D.N. Itzhak, L.A. Royer, M. Mann, M.D. Leonetti, "OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization," Science, 375, eabi6983 (2022). Journal Preprint Biohub OpenCell Portal
  18. M. Zarei, D. Xie, F. Jiang, A. Bagirov, B. Huang, A. Raj, S. Nagarajan, S. Guo, "High activity and high functional connectivity are mutually exclusive in resting state zebrafish and human brains," BMC Biology, 20, 84 (2022).
  19. W. Liu, W. Zhong, J. Chen, B. Huang, M. Hu, Y. Li, "Understanding regulatory mechanisms of brain function and disease through 3D genome organization," Genes, 13, 586 (2022).
  20. Y. Wang, H. Pinkard, E. Khwaja, S. Zhou, L. Waller, B. Huang, Image denoising for fluorescence microscopy by supervised to self-supervised transfer learning, Opt. Express 29, 41303-41312 (2021). Journal Preprint GitHub
  21. G.J. Kim, H. Mo, H. Liu, Z. Wu, S. Chen, J. Zheng, X. Zhao, D. Nucum, J. Shortland, L. Peng, M. Elepano, B. Tang, S. Olson, N. Paras, H. Li, A.R. Renslo, M.R. Arkin, B. Huang, B. Lu, M. Sirota, S. Guo, A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons, eLife 10, e69795 (2021).
  22. D. Kumar, A. Rains, V. Herranz-Pérez, Q. Lu, X. Shi, D.L. Swaney, E. Stevenson, N.J. Krogan, B. Huang, C. Westlake, J.M. Garcia-Verdugo, B.K. Yoder, J.F. Reiter, A ciliopathy complex builds distal appendages to initiate ciliogenesis, J. Cell Biol., 220, e202011133 (2021). Journal
  23. X. Shi, Q. Li, Z. Dai, A.A. Tran, S. Feng, A.D. Ramirez, Z. Lin, X. Wang, T.T. Chow, J. CHen, D. Kumar, A.R. McColloch, J.F. Reiter, E.J. Huang, I.B. Seiple, B. Huang, Label-retention expansion microscopy, J. Cell Biol., 220, e202105067 (2021). Journal Preprint
  24. X. Zhao, J.Q. Garcia, K. Tong, X. Chen, B. Yang, Q. Li, Z. Dai, X. Shi, I.B. Seiple, B. Huang, S. Guo, Polarized endosome dynamics engage cytoplasmic Par-3 that recruits dynein during asymmetric cell division, Sci. Adv., 7, eabg1244 (2021).
  25. B. Tenner, J.Z. Zhang, Y. Kwon, V. Pessino, S. Feng, B. Huang, S. Mehta, J. Zhang, FluoSTEPs: Fluorescent biosensors for monitoring compartmentalized signaling within endogenous microdomains, eLife, 7, eabe4091 (2021).
  26. A. Tulpule, J. Guan, D.S. Neel, H.R. Allegakoen, Y.P. Lin, D. Brown, Y. Chou, A. Heslin, N. Chatterjee, S. Perati, S. Menon, T.A. Nguyen, J. Debnath, A.D. Ramirez, X. Shi, B. Yang, S. Feng, S. Makhija, B. Huang, T.G. Bivona, Kinase-mediated RAS signaling via membraneless cytoplasmic protein, Cell 184, 2649-2664.e18 (2021). Journal Preprint Spotlight in Molecular Cell Highlight by Cancer Discovery
  27. S. Makhija, D. Brown, R.M. Rudlaff, J. Doh, S. Bourke, Y. Wang, S. Zhou, R. Cheloor-Kovilakam, B. Huang, Versatile labeling and detection of endogenous proteins using tag-assisted split enzyme complementation, ACS Chem. Biol. 16, 671-681 (2021). Journal Preprint
  28. G.E. Peng, V. Pessino, B. Huang, M. von Zastrow, Spatial decoding of endosomal cAMP signals by a metastable cytoplasmic PKA network, Nat. Chem. Biol. 17, 558-566 (2021).
  29. M.M. Keenen, D. Brown, L.D. Brennan, R. Renger, H. Khoo, C.R. Carlson, B. Huang, S.W. Grill, G.J. Narlikar, S. Redding, HP1 proteins compact DNA into mechanically and positionally stable phase separated domains, eLife 10, e64563 (2021). Journal
  30. H. Canaj, J.A. Hussmann, H. Li, K.A. Beckman, L. Goodrich, N.H. Cho, Y.J. Li, D.A. Santos, A. McGeever, E.M. Stewart, V. Pessino, M.A. Mandeger, C. Huang, L. Gan, B. Panning, B. Huang, J.S. Weissman, M.D. Leonetti. "Deep profiling reveals substantial heterogeneity of integration outcomes in CRISPR knock-in experiments external site". bioRxiv/841098 (2019) Preprint
  31. H. Li, K.A. Beckman, V. Pessino, Bo Huang, J.S. Weissman, M.D. Leonetti. "Design and sepcificity of long ssDNA donors for CRISPR-based knock-in". bioRxiv/178905 (2019). Preprint
  32. S. Zhou, S. Feng, D. Brown, B. Huang, Improved yellow-green split fluorescent proteins for protein labeling and signal amplification, PLoS ONE 15, e0242592 (2020). Journal Preprint
  33. J. Zhang, D. Velmeshev, K. Hashimoto, Y. Huang, J.W. Hofmann, X. Shi, J. Chen, A.M. Leidal, J.G. Dishart, M.K. Cahill, K.W. Kelley, S.A. Liddelow, W.W. Seeley, B.L. Miller, T.C. Walther, R.V. Farase Jr., J.P. Taylor, E.M. Ullian, B. Huang, J. Debnath, T. Wittmann, A.R. Kreigstein, E.J. Huang, Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency, Nature 588, 459-465 (2020).
  34. X. Huang, X. Shi, M. Hansen, I. Setiady, C. Nemeth, A. Celli, B. Huang, T. Mauro, M. Koval, T. Desai, Nanotopography enhances dynamic remodeling of tight junction proteins through cytosolic liquid complexes, ACS Nano 14, 13192–13202 (2020).
  35. S. Chaturvedi, J. Klein, N. Vardi, C. Bolovan-Fritts, M. Wolf, K. Du, L. Mlera, M. Calvert, N.J. Moorman, F. Goodrum, B. Huang, L.S. Weinberger, A molecular mechanism for probabilistic bet-hedging and its role in viral latency, Proc. Nat. Acad. Sci. USA 117, 17240-17248 (2020).
  36. S. Feng, A. Varshney, D. Coto Villa, C. Modavi, J. Kohler, F. Farah, S. Zhou, N. Ali, J.D. Müller, M. VanHoven, B. Huang, Bright split red fluorescent proteins for the visualization of endogenous proteins and synapses, Commun. Biol. 2, 344 (2019). Journal Preprint
  37. J.M. Alexander, J. Guan, B. Li, L. Maliskova, M. Song, Y. Shen, B. Huang, S. Lomvardas, O.D. Weiner, Live-cell imaging reveals enhancer-dependent Sox2 transcription in the absence of enhancer proximity, eLife 8, e41769 (2019).
  38. B. Yang, X. Chen, Y. Wang, S. Feng, V. Pessino, N. Stuurman, N.H. Cho, K.W. Cheng, S.J. Lord, L. Xu, D. Xie, R.D. Mullins, M.D. Leonetti, B. Huang, Epi-illumination SPIM for volumetric imaging with high spatial-temporal resolution, Nat. Methods 16, 501-504 (2019). Journal Preprint
  39. S. Das, The Extracellular RNA Communication Consortium, K.M. Ansel, M. Bitzer, X.O. Breakefield, A. Charest, D.J. Galas, M.B. Gerstein, M. Gupta, A. Milosavljevic, M.T. McManus, T. Patel, R.L. Raffai, J. Rozowsky, M.E. Roth, J.A. Saugstad, K. Van Keuren-Jensen, A.M. Weaver, L.C. Laurent, The Extracellular RNA Communication Consortium: Establishing foundational knowledge and technologies for extracellular RNA research, Cell, 177, 231-242 (2019).
  40. X. Shi, G. Garcia III, Y. Wang, J.F. Reiter, B. Huang, Deformed alignment of super-resolution images for semi-flexible structures in 3D, PLoS One 0212735 (2019). Journal Preprint
  41. Y. Wang, B. Yang, S. Feng, V. Pessino, B. Huang, Multicolor fluorescent imaging by space-constrained computational spectral imaging, Opt. Express 27, 5393 (2019). Journal Preprint
  42. B. Chen, W. Zou, H. Xu, Y. Liang, B. Huang, Efficient labeling and imaging of protein-coding genes in living cells using CRISPR-Tag, Nat. Commun. 9, 5065 (2018). Journal Preprint
  43. T.T. Chow, X. Shi, J.H. Wei, J. Guan, G. Stadler, B. Huang, E. Blackburn, Local enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection, Nat. Commun. 9, 3583 (2018). Journal
  44. M. Percharde, C. Lin, Y. Yin, J. Guan, G.A. Peixoto, A. Bulut-Karslioglu, S. Biechele, B. Huang, X. Shen, M. Ramalho-Santos, A LINE1-Nucleolin partnership regulates embryonic stem cell identity, Cell 174, 391-405 (2018). Journal
  45. G. Sepulveda, M. Antkowiak, I. Brust-Mascher, K. Mahe, T. Ou, N. Castro, L.N. Christensen, L. Cheung, D. Yoon, B. Huang, L.E. Jao, Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation, eLife 7, e34959 (2018). Journal Preprint
  46. M.T. Kelliher, Y. Yue, A. Ng, D. Kamiyama, B. Huang, K.J. Verhey, J. Wildonger, Autoinhibition of kinesin-1 is essential to the dendrite-specific localization of Golgi outposts, J. Cell Biol. 217, 2531-2547 (2018).
  47. J. Schnitzbauer, Y. Wang, M. Bakalar, B. Chen, T. Nuwal, S. Zhao, B. Huang, Correlation analysis framework for localization-based superresolution microscopy, Proc. Nat. Acad. Sci. USA 115, 3219-3224 (2018). Journal Preprint Research Highlights in Nat. Methods
  48. P. Viswanath, M. Radoul, J.L. Izquierdo-Garcia, W.Q. Ong, H.A. Luchman, J.G. Cairncross, B. Huang, R.O. Pieper, J.J. Phillips, S.M. Ronen, 2-hydroxyglutarate-mediated autophagy of the endoplasmic reticulum leads to an unusual downregulation of phospholipid biosynthesis in mutant IDH1 gliomas, Cancer Res. 78, 2290-2304 (2018).
  49. Y.R. Citron, Y.R. Citron, C.J. Fagerstrom, B. Keszthelyi, B. Huang, N.M. Rusan, M.J.S. Kelly, D.A. Agard, The centrosomin CM2 domain is a multi-functional binding domain with distinct cell cycle roles, PLoS One 13, e0190530 (2018). Journal Preprint
  50. X. Shi, G. Garcia, J.C. Van De Weghe, R. McGorty, G.J. Pazour, D. Doherty, B. Huang, J.F. Reiter, Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert syndrome, Nat. Cell Biol. 19, 1178-1188 (2017). Journal Preprint
  51. R. McGorty, D. Xie, B. Huang, High-NA open-top selective-plane illumination microscopy for biological imaging, Opt. Express, 25, 17798-17810 (2017). Journal Preprint
  52. S. Feng, S. Sekine, V. Pessino, H. Li, M.D. Leonetti, B. Huang, Improved split fluorescent proteins for endogenous protein labeling, Nat. Commun., 8, 370 (2017). Journal Preprint Tools in Brief by Nat. Methods
  53. Q. Li, M. Reinig, D. Kamiyama, X. Tao, B. Huang, J. Kubby, Woofer-tweeter adaptive optical structured illumination microscopy, Photonics Res., 5, 329-334 (2017).
  54. V. Pessino, Y.R. Citron, S. Feng, B. Huang, Covalent protein labeling by SpyTag-SpyCatcher in fixed cells for super-resolution microscopy, ChemBioChem, 18, 1942-1945 (2017). Journal Preprint
  55. R. Irannejad, V. Pessino, D. Mika, B. Huang, P.B. Wedegaertner, M. Conti, M. von Zastrow, Functional selectivity of GPCR-directed drug action through location bias, Nat. Chem. Biol. 13, 799-806 (2017). Journal
  56. B. van Lengerich, E.M. Puchner, C. Angew, B. Huang, N. Jura, EGF and NRG induce phosphorylation of HER3/ERBB3 by EGFR using distinct oligomeric mechanisms, Proc. Nat. Acad. Sci. USA 114, E2836-3845 (2017). Journal
  57. J. Guan, H. Liu, X. Shi, S. Feng, B. Huang, Tracking multiple genomic elements using correlative CRISPR imaging and sequential DNA FISH, Biophys. J., 112, 1077-1084 (2017). Journal Preprint New and Notable
  58. W.Q. Ong, Y.R. Citron, S. Sekine, B. Huang, Live cell imaging of endogenous mRNA using RNA-based fluorescence “turn-on” probe, ACS Chem. Biol., 12, 200-205 (2017). Journal
  59. B. Huang, A microscopic view of the cell, Mol. Biol. Cell, 27, 3183-3184 (2016).
  60. L. Zhu, B. Huang, STORM using compressed sensing, in Adrian Stern, editor: Optical Compressive Sensing, CRC Press, pp. 225-238 (2016).
  61. H. Liu, S. Chen, K. Huang, J. Jim, H. Mo, R. Iovine, J. Gendre, P. Pascal, Q. Li, Z. Dong, M. Arkin, S. Guo, B. Huang, A high-content larval zebrafish brain imaging method for small molecule drug discovery, PLoS One, 11, e0164645 (2016). Journal
  62. Y. Bai, H. Liu, B. Huang, M. Wagle, S. Guo, Identification of environmental stressors and validation of light preference as a measure of anxiety in larval zebrafish, BMC Neurosci., 17, 63 (2016). Journal
  63. M.D. Leonetti, S. Sekine, D. Kamiyama, J.S. Weissman, B. Huang, A scalable strategy for high-throughput GFP tagging of endogenous human proteins, Proc. Nat. Acad. Sci. USA, 113, E3501-E3508 (2016). Journal Preprint
  64. B. Chen, J. Guan, B. Huang, Imaging specific genomic DNA in living cells, Ann. Rev. Biophys., 45, 1-23 (2016).
  65. R. McGorty, B. Huang, Selective-plane illumination microscopy for high-content volumetric biological imaging , Proc. SPIE, 9720, 97200P, doi:10.1117/12.2212889 (2016). Preceedings
  66. D. Kamiyama, S. Sekine, B. Barsi-Rhyne, J. Hu, B. Chen, L.A. Gilbert, H. Ishikawa, M.D. Leonetti, W.F. Marshall, J.S. Weissman, B. Huang, Versatile protein tagging in cells with split fluorescent protein, Nat. Commun., 7, 11046 (2016). Journal
  67. P. Bieling, T.D. Li, J. Weichsel, R. McGorty, P. Jreij, B. Huang, D.A. Fletcher, R.D. Mullins, Force feedback controls motor activity and mechanical properties of self-assembling branched actin networks, Cell, 164, 115-127 (2016). Journal
  68. B. Chen, J. Hu, R. Almeida, H. Liu, S. Balakrishnan, C. Covill-Cooke, W.A. Lim, B. Huang, Expanding the CRISPR imaging toolset with Staphylococcus aureus Cas9 for simultaneous imaging of multiple genomic loci, Nucleic Acids Res., 44, e75 (2016). Journal
  69. D. Kamiyama, R. McGorty, R. Kamiyama, M.D. Kim, A. Chiba, B. Huang, Specification of dendritogenesis site in Drosophila aCC motoneuron by membrane-enrichment of Pak1 through Dscam1, Dev. Cell, 35, 93-106 (2015). Journal
  70. J.G. Patton, J.L. Franklin, A.M. Weaver, K. Vickers, B. Zhang, R.J. Coffey, K.M. Ansel, R. Blelloch, A. Goga, B. Huang, N. L'Etoille, R. Raffai, C.P. Lai, A.M. Krichevsky, B. Mateescu, V.J. Greiner, C. Hunter, O. Voinnet, M.T. McManus, Biogenesis, delivery and function of extracellular RNA, J. Extracellular Vesicles, 4, 27494 (2015).
  71. W.Q. Ong, Y.R. Citron, J. Schnitzbauer, D. Kamiyama, B. Huang, Heavy water: a simple solution to increasing brightness of fluorescence protein in super-resolution imaging, Chem. Commun., 51, 13451 - 13453 (2015). Journal
  72. R. McGorty, H. Liu, D. Kamiyama.Z. Dong, S. Guo, B. Huang, Open-top selective plane illumination microscope for conventionally mounted specimens, Opt. Express, 23, 16142-16153 (2015). Journal
  73. B. Chen, B. Huang, Imaging genomic elements in living cells using CRISPR/Cas9. In J.A. Doudna, E.J. Sontheimer, editors: The use of CRISPR/cas9, ZFNs, TALENs in generating site specific genome alterations, Vol 546, MIE, UK: Academic Press, pp. 337-354 (2014).
  74. E. Puchner, B. Huang, H. Gaub, Single molecule techniques - applications in biology, FEBS Lett., 588, 3519 (2014).
  75. Y. Wang, J. Schnitzbauer, Z. Hu, X. Li, Y. Cheng, Z.L. Huang, B. Huang, Localization events-based sample drift correction for localization microscopy with redundant cross-correlation algorithm, Opt. Express, 22, 15982-15991 (2014). Journal
  76. S. Sun, C. Zhou, S. Chen, J. Liu, J. Yu, J. Chilek, L. Zhao, M. Y, R. Vinluan, B. Huang, J. Zheng, Surface-chemistry effect on cellular response of luminescent plasmonic silver nanoparticles, Bioconjugate Chem., 25, 453-458 (2014).
  77. R. McGorty, J. Schnitzbauer, W. Zhang, B. Huang, Correction of depth-dependent aberrations in 3D single molecule localization and super-resolution microscopy. Opt. Lett., 39, 275-278 (2014). Journal
  78. B. Chen, L.A. Gilbert, B.A. Cimini, J. Schnitzbauer, W. Zhang, G.W. Li, J. Park. E.H. Blackburn, J.S. Weissman, L.S. Qi, B. Huang, Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system. Cell, 155, 1479-1491 (2013). Journal Feature in BioTechnique
  79. V. Mennella, D.A. Agard, B. Huang, L. Pelletier, Amorphous no more: subdiffraction view of the pericentriolar material architecture. Trends Cell Biol. 24, 188-197. (2014).
  80. E.M. Puchner, J.M. Walter, R. Kasper, B. Huang, W.A. Lim, Counting molecules in single organelles with superresolution microscopy allows tracking of the endosome maturation trajectory. Proc. Nat. Acad. Soc. USA, 110, 16015-16020 (2013). Journal
  81. J. Schnitzbauer, R. McGorty, B. Huang, 4Pi fluorescence detection and 3D particle localization with a single objective. Opt. Express, 21, 19701-19708 (2013). Journal Feature in Laser Focus World
  82. F. Huang, X. Wang, E.M. Ostertag, T. Nuwal, B. Huang, Y.N. Jan, A.I. Basbaum and L.Y. Jan, TMEM16C facilitates Na(+)-activated K(+) currents in rat sensory neurons and regulates pain processing. Nat. Neurosci., 16, 1284-1290 (2013). Journal
  83. R. McGorty, D. Kamiyama, B. Huang, Active microscope stabilization in three dimensions using image correlation. Optical Nanoscopy, 2, 3 (2013). Journal
  84. R. Irannejad, J.C. Tomshine, J.R. Tomshine, M. Chevalier, J. Steyaert, S.G.F. Rasmussen, H. El-Samad, B. Huang, M. von Zastrow, Conformational biosensors reveal adrenoceptor signaling from endosomes. Nature, 459, 534-538 (2013). Journal News and News in Nature 2013 Methods to Watch by Nat. Methods
  85. A.S. Stender, K. Marchuk, C. Liu, S. Sander, M.W. Meyer, E.A. Smith, B. Neupane, G. Wang, J. Li, J.X. Cheng, B. Huang, N. Fang, Single cell optical imaging and spectroscopy, Chem. Rev., 113, 2469-2527 (2013).
  86. D. Kamiyama B. Huang, Development in the STORM. Developmental Cell, 23, 1103 (2012)
  87. V. Mennella, B. Keszthelyi, K.L. McDonald, B. Chhun, F. Kan, G.C. Rogers, B. Huang, D.A. Agard, Subdiffraction-resolution fluorescence microscopy reveals a domain of the centrosome critical for pericentriolar material organization. Nat. Cell Biol., 14, 1159-1168 (2012). Journal News and Views
  88. S.H. Shim, C. Xia, G. Zhong, H.P. Babcock, J.C. Vaughan, B. Huang, X. Wang, C. Xu, G.Q. Bi, X. Zhuang, Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes. Proc. Nat. Acad. Sci. USA, 109, 13978-3983 (2012).
  89. L. Zhu, W. Zhang, D. Elnatan, B. Huang, Faster STORM with compressed sensing. Nat. Methods, 9, 721-723 (2012). Journal News and Views
  90. R. Kasper, B. Huang, SnapShot: Light Microscopy. Cell, 147, 1198 (2011).
  91. G.M.J. Beaudoin, III, G.M. Schofield, T. Nuwal, K. Zang, E.M. Ullian, B. Huang, L.F. Reichardt, Afadin, a Ras/Rap effector that controls cadherin function, promotes spine and excitatory synapse density in the hippocampus. J Neurosci., 32, 99-110 (2012). Journal
  92. B. Huang, An in-depth view. Nat Methods, 8, 304-305 (2011).
  93. B. Huang, H. Babcock, X. Zhuang, Breaking the diffraction barrier: super-resolution imaging of cells. Cell, 143, 1047-1058 (2010).
  94. A. Dani, B. Huang, J. Bergan, C. Dulac, X. Zhuang, Superresolution imaging of chemical synapses in the brain. Neuron, 68, 843-856 (2010).
  95. A. Dani, B. Huang, New resolving power for light microscopy: applications to neurobiology. Curr. Opin. Neurobiol., 20, 648-652 (2010).
  96. M. Wu, B. Huang, M. Graham, A. Raimondi, J.E. Heuser, X. Zhuang, P. De Camilli, Coupling between clathrin-dependent budding and F-BAR-dependent membrane tubulation in a cell-free system of endocytosis. Nat. Cell. Biol., 12, 902-908 (2010).
  97. B. Huang, Super resolution optical microscopy: multiple choices. Curr. Opin. Chem. Biol., 14, 10-14 (2010).
  98. B. Huang, M. Bates, X. Zhuang, Super resolution fluorescence microscopy. Ann. Rev. Biochem., 78, 993-1016 (2009).
  99. M. Bates, B. Huang, X. Zhuang, Super-resolution imaging by nanoscale localization of photo-switching fluorescent probes. Curr. Opin. Chem. Biol., 12, 505-514 (2008).
  100. B. Huang, S.A. Jones, B. Brandenburg, X. Zhuang, Whole cell 3D STORM reveals interactions between cellular structures with nanometer-scale resolution. Nat. Methods, 5, 1047-1052 (2008).
  101. B. Huang, W. Wang, M. Bates, X. Zhuang, Three-dimension super-resolution imaging by stochastic optical reconstruction microscopy. Science, 319, 810-813 (2008).
  102. M. Bates, B. Huang, G.T. Dempsey, X. Zhuang, Multicolor super-resolution imaging with photo-switchable fluorescent probes. Science, 317, 1749-1753 (2007).
  103. B. Huang, H. Wu, D. Bhaya, A.R. Grossman, S. Granier, B.K. Kobilka, R.N. Zare, Counting low-copy-number proteins in a single cell. Science, 315, 81-84 (2007).
  104. S. Kim, B. Huang, H. Wu, R.N. Zare, Microfluidic separation and capture of analytes for single-molecule spectroscopy. Lab Chip, 7, 1663-1665 (2007).
  105. B. Huang, S. Kim, R.N. Zare, Use of a mixture of n-dodecyl-β-D-maltoside and sodium dodecyl sulfate in poly (dimethylsiloxane) microchips to suppress adhesion and promote separation of proteins. Anal. Chem., 79, 9145-9149 (2007).
  106. M.R. Whorton, M.P. Bokoch, S.G. F. Rasmussen, A. Kuszak, B. Huang, R.N. Zare, B.K. Kobilka, R.K. Sunahara, A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein. Proc. Nat. Acad. Sci. U.S.A., 104, 7682-7687 (2007).
  107. B. Huang, F. Yu, R.N. Zare, Surface plasmon resonance imaging using a high numerical aperture microscope objective. Anal. Chem., 79, 2979-2983 (2007).
  108. H. Wu, B. Huang, R.N. Zare, Generation of complex, static solution gradients in microfluidic channels. J. Am. Chem. Soc., 128, 4194-4195 (2006).
  109. Y. Luo, B. Huang, H. Wu, R.N. Zare, Controlling electroosmotic flow in polydimethylsiloxane (PDMS) separation channels by means of prepolymer additives. Anal. Chem., 78, 4588-4592 (2006).
  110. B. Huang, H. Wu, S. Kim, B.K. Kobilka, R.N. Zare, Phospholipid biotinylation of polydimethylsiloxane (PDMS) for protein immobilization. Lab Chip, 6, 369-373 (2006).
  111. H. Wu, B. Huang, R.N. Zare, Construction of microfluidic chips using polydimethylsiloxane for adhesive bonding. Lab Chip, 5, 1393-1398 (2005).
  112. B. Huang, H. Wu, S. Kim, R.N. Zare, Coating of poly(dimethylsiloxane) with n-dodecyl-beta-D-maltoside to minimize nonspecific protein adsorption. Lab Chip, 5, 1005-1007 (2005).
  113. T.D. Perroud, B. Huang, R.N. Zare, Effect of bin time on the photon counting histogram for one-photon excitation. ChemPhysChem, 6, 905-912 (2005).
  114. B. Huang, T.D. Perroud, R.N. Zare, Photon counting histogram: one-photon excitation. ChemPhysChem, 5, 1523-1531 (2004).
  115. T.D. Perroud, B. Huang, M.I. Wallace, R.N. Zare, Photon counting histogram for one-photon excitation. ChemPhysChem, 4, 1121-1123 (2003).
  116. R.J. Whelan, T. Wohland, L. Neumann, B. Huang, B. K Kobilka, R. N Zare, Analysis of bimolecular interactions using a miniaturized surface plasmon resonance sensor. Anal. Chem., 74, 4570-4576 (2002).
  117. L. Ying, X. Huang, B. Huang, J. Xie, J. Zhao, X. Zhao, Fluorescence emission and absorption spectra of single Anabaena sp strain PCC7120 cells. Photochem. Photobio., 76, 310-313 (2002).
  118. L. Ying, X. Huang, B. Huang, J. Zhao, X. Zhao, Spectra of single cyanobacterial cells. Acta Physico-Chimica Sinica, 18, 673-675 (2002).
  119. B. Huang, Y. Yang, Treatment of experimental data of surface adsorption in solution by computer linear fitting method. University Chemistry, 17, 51 (2002).