Bo Huang          Curriculum vitae         Full Version

1700 4th St, MC 2532
Byers Hall 303A
San Francisco, CA 94158

Tel: (415) 476-1866
Fax: (415) 502-8298
Email:  

Employment

Assistant Professor, Department of Pharmaceutical Chemistry and
     Department of Biochemistry and Biophysics, UCSF
2009

Academic Training

Harvard University
    Postdoctoral Fellow                                  Mentor: Xiaowei Zhuang
2006-2009
Stanford University
    Ph.D. in Chemistry                                    Advisor: Richard N. Zare
    Thesis: Chemical analysis of single cells
2001-2006
Peking University, China
    B.S. in Chemistry summa cum laude        Advisor: Zhao Xinsheng
1997-2001

Honors Received

♦    NIH Director's New Innovator Award 2011
♦    Packard Fellowship for Science and Engineering 2010
♦    Searle Scholars 2010
♦    GE & Science Young Life Scientist Prize
      North American Regional Winner
2007
♦    Annual Reviews Prize in Physical Chemistry, Stanford University 2006
♦    Stanford Graduate Fellowship 2001-2004
♦    Rado Young Genius Prize in China, First Place 1996

Selected Publications

  • 31. L. Zhu, W. Zhang, D. Elnatan, B. Huang, “Faster STORM with compressed sensing”, Nat. Methods, doi: 10.1038/nmeth.1978 (2012).
  • 29. G.M.J. Beaudoin, III, G.M. Schofield, T. Nuwal, K. Zang, E.M. Ullian, B. Huang, L.F. Reichardt, “Afadin, a Ras/Rap effector that controls cadherin function, promotes spine and excitatory synapse density in the hippocampus”, J. Neurosci., 32, 99-110 (2012).
  • 27. B. Huang, H. Babcock, X. Zhuang, “Breaking the diffraction barrier: super-resolution imaging of cells”, Cell, 143, 1047-1058 (2010).
  • 26. A. Dani, B. Huang, J. Bergan, C. Dulac, X. Zhuang, “Superresolution imaging of chemical synapses in the brain”, Neuron, 68, 843-856 (2010).
  • 24. M. Wu, B. Huang, M. Graham, A. Raimondi, J.E. Heuser, X. Zhuang, P. De Camilli, “Coupling between clathrin-dependent budding and F-BAR-dependent membrane tubulation in a cell-free system of endocytosis”, Nat. Cell. Biol., 12, 902-908 (2010).
  • 22. B. Huang, M. Bates, X. Zhuang, “Super resolution fluorescence microscopy”, Ann. Rev. Biochem., 78, 993-1016 (2009).
  • 20. B. Huang, S. A. Jones, B. Brandenburg, X. Zhuang, “Whole cell 3D STORM reveals interactions between cellular structures with nanometer-scale resolution”, Nat. Methods, 5, 1047-1052 (2008).
  • 19. B. Huang, W. Wang, M. Bates, X. Zhuang, “Three-dimension super-resolution imaging by stochastic optical reconstruction microscopy”, Science, 319, 810-813 (2008).
  • 18. M. Bates, B. Huang, G. T. Dempsey, X. Zhuang, “Multicolor super-resolution imaging with photo-switchable fluorescent probes”, Science, 317, 1749-1753 (2007).
  • 17. B. Huang, H. Wu, D. Bhaya, A. R. Grossman, S. Granier, B. K. Kobilka, R. N. Zare, “Counting low-copy-number proteins in a single cell”, Science, 315, 81-84 (2007).
  • 15. B. Huang, S. Kim, R. N. Zare, “High performance electrophoretic analysis of proteins in a polydimethylsiloxane microchip using mixed surfactants of n-dodecyl-β-D-maltoside and sodium dodecylsulfate”, Anal. Chem., 79, 9145-9149 (2007).
  • 14. M. R. Whorton, M. P. Bokoch, S. G. F. Rasmussen, A. Kuszak, B. Huang, R. N. Zare, B. K. Kobilka, R. K. Sunahara, “Monomeric β2 adrenergic receptors in lipid bilayers couple to G proteins and display allosteric regulation of agonist binding”, Proc. Nat. Acad. Sci. U.S.A., 104, 7682-7687 (2007).
  • 13. B. Huang, F. Yu, R. N. Zare, “Surface plasmon resonance imaging using a high numerical aperture microscope objective”, Anal. Chem., 79, 2979-2983 (2007).
  • 10. B. Huang, H. Wu, S. Kim, B. K. Kobilka, R. N. Zare, “Phospholipid biotinylation of polydimethylsiloxane (PDMS) for protein immobilization”, Lab Chip, 6, 369-373 (2006).
  • 8. B. Huang, H. Wu, S. Kim, R. N. Zare, “Coating of poly(dimethylsiloxane) with n-dodecyl-beta-D-maltoside to minimize nonspecific protein adsorption”, Lab Chip, 5, 1005-1007 (2005).
  • 6. B. Huang, T. D. Perroud, R. N. Zare, “Photon counting histogram: one-photon excitation”, ChemPhysChem, 5, 1523-1531 (2004).

Professional Activities

  • Member, Biophysical Society (2002-Date)
  • Member, American Chemistry Society (2005-Date)
  • Member, American Society of Cell Biology (2008-Date)
  • Journal Reviewer: Cell, Nature, Nature Methods, Nature Biotechnology, Journal of American Chemical Society, Structure, Nano Letter, Nanoscale, Journal of Molecular Biology, Biophysical Journal, Optics Letter, Microscopy Research and Technique