Watching the inner life of a cell

Cellular processes are orchestrated by a large number of biomolecules in a spatially and temporally coordinated manner within a tiny volume. To uncover the underlying organizational principles and their functional relevance, we take microscopy visualization as the primary approach to systematically map the spatial localization, temporal dynamics and activity profiles of proteins and nucleic acids.


We are particularly interested in the following problems:

In order to study these systems, we are developing the following microscopy technologies:


Research updates

(Nat. Commun. 2018)
STORM images
(PNAS 2018)
Molecular architecture of
ciliary transition zone
(Nat. Cell. Biol. 2017)

Lab updates...