Watching the inner life of a cell
      

Cellular processes are orchestrated by a large number of protein and nucleic acid molecules in a small volume. In order to elucide how these molecules work together, we take a microscopy approach that systematically maps their spatial organization, activity profile and temporal dynamics.

 

We are particularly interested in the following problems:
 

In order to study these systems, we are developing the following microscopy technologies:
 

 

Research updates

Creating a GFP knock-in library (PNAS 2016) Protein labeling using FP11 tags (Nat. Comm. 2016) Multi-color CRISPR imaging (Nucleic Acids Res. 2016)

Lab updates...